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:: bioinformatics introduction ::
 | Post date: 2015/02/22 | 
Bioinformatics is about using information technology to manage molecular biological data. These biological data in many cases come from experiments done by biologists in wet lab. It means people working with bioinformatics must have knowledge in both computer science and biology. Actually bioinformatics is to use computer and software to collect, organize and store biological data in databases. It's also development of computer programs for analyzing biological data.
 In general bioinformatics can be:
 Focusing on using existing bioinformatics tools for analyzing and delivering new biological findings and developing new bioinformatics algorithms and tools or improving the existing ones.

 How did bioinformatics develop? Here is a brief selection of events in the history of the field:
 - Until early 1970s biologists had to compare DNA and protein sequences manually
- Needleman and Wunsch in 1970 published the first computer algorithm for sequence comparison and alignment
 -In 1971 the Brookhaven Protein Data Bank was founded, which holds data about the 3D structure of proteins
 - The1970s saw the first attempts to use computers to predict protein secondary structure prediction
- In 1978, the term “bioinformatics” was used for the first time, and defined as "studies of informatics processes in biotic systems
 -In 1980 Smith and Waterman published an improved, and very influential, algorithm for pairwise sequence comparison and alignment
- In 1983 PCR was invented- In 1986 the SWISS-PROT database was founded, holding annotated protein sequence
 -In 1986 the FASTA algorithm was published, which made it possible to speed up sequence comparison and handle rapidly growing amounts of sequence data
 -In 1990 the BLAST program was released, which allows similarity search in databases containing several million sequences
-In 1991 the use of Expressed Sequence Tags described, opening the possibility of sequencing all expressed genes in an organism (the transcriptom) in a single experiments -In 1995 the first microarray for gene expression profiling become available
 -In 1996 the PROSITE database of protein motifs released
 -In 1997 the complete genome sequence of C.elegans was published
 -In 2001 the first draft of the human genome sequence was published
 -Since 2002 the rat, mouse, malaria and chimpanzee genomes have been published, as well as many other important eukaryotic genomes
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انجمن علمی بیوانفورماتیک ایران Iranian Bioinformatics Society (IBIS)
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